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Depressive Disorder


Insomnia and Mood Disorders in Adolescents

Insomnia and sleep disturbance are common symptoms of depression in adults, but this is not always the case in adolescents. In fact, a group of researchers at the University of Pittsburgh who studied insomnia in depressed teens found that, compared to adults, insomnia in adolescents is different—very different.

Editor’s Perspective: Do Antidepressants Work in Kids?

The extent to which antidepressants are effective for pediatric depression continues to stir controversy, as discussed in this issue of CCPR.

Treating Depressed Adolescents Who Have Attempted Suicide: Results of the TASA Trial

Historically, research into the effectiveness of antidepressants for depressed youths has been unimpressive. The history of SSRI use in children has been fraught with its own series of disappointments and controversies.

Research Update

Girls More Likely to Have Recurrent Depression

The Treatment for Adolescents With Depression Study (TADS) taught us that fluoxetine (Prozac)
plus cognitive behavioral therapy was superior to medication alone or placebo for short-term recovery from major depressive disorder (MDD). But TADS didn’t tell us anything about long-term recovery.

Acne Increases Suicide Risk, With or Without Accutane

Despite having been around for 30 years, there is still controversy surrounding the acne drug isotretinoin (Accutane) and its association with psychiatric problems.