Antidepressants

Article

Antidepressants and Suicidal Ideation in Young People: A Practical Approach

In October of 2004, the FDA announced to drug companies that they should add black-box warnings about the risk of suicidal behavior in children and adolescents started on antidepressants. How have these black-box warnings affected clinical practice over the past decade?

Dealing With Side Effects of SSRIs

Selective serotonin reuptake inhibitors (SSRIs) are widely used as the first-line treatment for depression and anxiety in children and adolescents, but they are associated with significant adverse effects (AEs). Studies have shown that up to 50% of kids experience side effects from SSRIs, depending on the sample size and the type of study. 

Future Developments in Antidepressant Therapy

In 2011 in the pages of TCPR, we asked, “What’s new in antidepressant treatment?” The answer was “not much” (TCPR, April 2011). In 2012, unfortunately, the answer isn’t very different.

Research Update

Does Dose Matter When it Comes to Antidepressants and Self-Harm?

Concerns about the possible risk of suicide in young people taking antidepressants are often voiced by experts and parents. But how much of a role does dosage play in the risk of suicide and self-harm among young people on antidepressants?